全文获取类型
收费全文 | 474篇 |
免费 | 34篇 |
国内免费 | 1篇 |
出版年
2022年 | 6篇 |
2021年 | 10篇 |
2020年 | 5篇 |
2019年 | 5篇 |
2018年 | 18篇 |
2017年 | 10篇 |
2016年 | 20篇 |
2015年 | 28篇 |
2014年 | 34篇 |
2013年 | 19篇 |
2012年 | 35篇 |
2011年 | 26篇 |
2010年 | 16篇 |
2009年 | 14篇 |
2008年 | 20篇 |
2007年 | 12篇 |
2006年 | 18篇 |
2005年 | 17篇 |
2004年 | 14篇 |
2003年 | 11篇 |
2002年 | 6篇 |
2001年 | 10篇 |
2000年 | 7篇 |
1999年 | 11篇 |
1998年 | 6篇 |
1997年 | 7篇 |
1996年 | 3篇 |
1995年 | 4篇 |
1994年 | 7篇 |
1992年 | 7篇 |
1991年 | 9篇 |
1990年 | 4篇 |
1989年 | 7篇 |
1988年 | 6篇 |
1987年 | 5篇 |
1985年 | 7篇 |
1984年 | 6篇 |
1983年 | 5篇 |
1982年 | 6篇 |
1980年 | 4篇 |
1979年 | 3篇 |
1976年 | 3篇 |
1975年 | 5篇 |
1974年 | 3篇 |
1973年 | 6篇 |
1971年 | 3篇 |
1970年 | 3篇 |
1969年 | 2篇 |
1968年 | 2篇 |
1967年 | 3篇 |
排序方式: 共有509条查询结果,搜索用时 281 毫秒
51.
Kleber Queiroz FerreiraAngélica Maria Lucchesi Zênis Novais da RochaRoberto Santana da Silva 《Inorganica chimica acta》2002,328(1):147-151
We report here the synthesis, characterization and kinetic studies of cis-[RuCl2(cyclen)]+ in aqueous solution, where cyclen is the macrocyclic ligand 1,4,7,10-tetraazacyclododecane. The complex releases one Cl− producing cis-[RuCl(OH)(cyclen)]+ in aqueous solution at pH 4.60. The product of this reaction was characterized by Ultraviolet-Visible (UV-Vis) spectrum in comparison to the synthesized cis-[RuCl(OH)(cyclen)](BF4)·2H2O. The electrochemical data showed that Epc of the Ru(III/II) peak increases as the macrocycle ring size decreases and also when the trans conformation is changed to cis. The chloride affinity of Ru(III) depends on the macrocycle ring size since cis-[RuCl2(cyclam)]+ (cyclam=1,4,8,11-tetraazacyclotetradecane) does not release chloride for at least 12 h. The overall effect between cyclam and cyclen reflects the fact that the electron involved in the reduction enters a nonbonding π-d orbital and its energy is affected by the macrocyclic ligand. 相似文献
52.
53.
54.
55.
Paula A. Rudenick Bart H. Bijnens Patrick Segers David García-Dorado Arturo Evangelista 《PloS one》2015,10(4)
Descending aortic dissection (DAD) is associated with high morbidity and mortality rates. Aortic wall stiffness is a variable often altered in DAD patients and potentially involved in long-term outcome. However, its relevance is still mostly unknown. To gain more detailed knowledge of how wall elasticity (compliance) might influence intraluminal haemodynamics in DAD, a lumped-parameter model was developed based on experimental data from a pulsatile hydraulic circuit and validated for 8 clinical scenarios. Next, the variations of intraluminal pressures and flows were assessed as a function of wall elasticity. In comparison with the most rigid-wall case, an increase in elasticity to physiological values was associated with a decrease in systolic and increase in diastolic pressures of up to 33% and 63% respectively, with a subsequent decrease in the pressure wave amplitude of up to 86%. Moreover, it was related to an increase in multidirectional intraluminal flows and transition of behaviour as 2 parallel vessels towards a vessel with a side-chamber. The model supports the extremely important role of wall elasticity as determinant of intraluminal pressures and flow patterns for DAD, and thus, the relevance of considering it during clinical assessment and computational modelling of the disease. 相似文献
56.
57.
58.
59.
60.
Paula Gonçalves Viana Anna Barreto Fernandes Figueiredo Isabella Dib Ferreira Gremião Luisa Helena Monteiro de Miranda Isabela Maria da Silva Antonio Jéssica Sepulveda Boechat Ana Caroline de Sá Machado Manoel Marques Evangelista de Oliveira Sandro Antonio Pereira 《Mycopathologia》2018,183(2):471-478
Sporotrichosis occurs worldwide, and the metropolitan region of Rio de Janeiro, Brazil, is a main endemic area, with a large number of human and animal cases in the last 19 years. This mycosis is more frequently described in cats rather than in dogs. There are a limited number of oral antifungal agents for the treatment of sporotrichosis in animals. In this context, the effectiveness of terbinafine in the treatment of sporotrichosis in humans, as well as the promising results of in vitro susceptibility tests, inspired us to use this drug in the therapy of this mycosis in dogs. We reported for the first time the use of terbinafine in the treatment of two dogs with sporotrichosis caused by Sporothrix brasiliensis. Moreover, we provided an overview of therapeutic features of canine sporotrichosis cases reported since the 1960s. One of the dogs presented the fixed cutaneous form of the disease, while the other patient presented hyperemia of the nasal mucosa and respiratory signs only. Terbinafine showed high antifungal activity in vitro against the canine Sporothrix isolates. The dogs were successfully treated with terbinafine, with remission of all clinical signs initially presented. The current reports indicate that this drug can emerge as a therapeutic option for canine sporotrichosis. 相似文献